TB-500, by prescription.
Starting from
No membership fee.
Free online visit. You only pay when prescribed.
Pharmacy-made TB-500, prescribed to you. A US-licensed physician (MD) reviews your history online, most within 24 hours, and a licensed US pharmacy compounds your vial with your name on the label. Your online visit is free.
- Compounded in the USA by licensed 503A pharmacies and FDA-registered facilities
- Single-ingredient TB-500 acetate
- A physician (MD) prescribes
- Subcutaneous or intramuscular injection
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
Can a clinician prescribe TB-500 now?
Yes. Since October 30, 2026, an HHS policy lets licensed 503A pharmacies compound TB-500 acetate for a patient with a prescription, under ten conditions. The policy is enforcement discretion, which is different from FDA approval, and HHS can revise it. Your clinician decides whether TB-500 is right for you.
Important safety information
Compounded TB-500 is not an FDA-approved drug, and FDA has not reviewed it for safety or effectiveness. It is prepared by a licensed 503A pharmacy for one patient and dispensed only on a clinician's prescription. TB-500 is on the World Anti-Doping Agency's prohibited list.
What it is
A fragment of a protein your cells already make
Thymosin beta-4 is a 43-amino-acid protein found in nearly every cell in the body. TB-500 is a seven-amino-acid piece of it, the stretch researchers call its active site, made by peptide synthesis.
Until now, most TB-500 sold online was labeled "for research use only," with no prescription, no clinician and no pharmacy label. HHS wrote its October 2026 policy to give patients "a more controlled alternative" to research-use-only peptides from foreign manufacturers.
Under that policy, a licensed 503A pharmacy can compound TB-500 acetate for you on a clinician's prescription. Your vial holds TB-500 and nothing else, labeled with your name, and your clinician sets the dose.
How it works
What the research looks at
Actin, the cell's scaffolding
Thymosin beta-4 binds actin, the protein cells use to move and change shape. Researchers study it because cells moving into place is an early step in tissue repair.
Most research used the full protein
Most published studies looked at full-length thymosin beta-4, mostly in animals. TB-500 is its seven-amino-acid fragment. Your clinician weighs what that research does and does not tell you.
One ingredient, one injection
The policy covers single-ingredient TB-500 acetate, given as a subcutaneous or intramuscular injection with an FDA-cleared syringe, on the schedule your clinician sets.
From the molecule to your vial
The molecule
Seven amino acids
TB-500 is the active-site fragment of thymosin beta-4, a protein found in nearly every human cell.
The research
Studied for cell movement
Animal studies of thymosin beta-4 have looked at how cells migrate and how new capillaries form during repair.
The policy
October 30, 2026
HHS published a policy allowing licensed 503A pharmacies to compound TB-500 acetate for a named patient, under ten conditions.
The pharmacy
Tested before it's compounded
The ingredient comes from an FDA-registered facility with a certificate of analysis for identity, purity, endotoxins and heavy metals.
Your clinician
Reviewed by a US-licensed clinician
A US-licensed clinician reads your history and decides whether TB-500 fits you, and at what dose.
Educational. Compounded TB-500 is prepared by a licensed 503A pharmacy in the USA and is not an FDA-approved drug.
What to expect
Four steps, all online.
Here is everything that happens between this page and your first vial.
Clinician-led- 1Clinician-ledWhat are you hoping TB-500 helps with?Getting back to training after a setback.
Free visit
Tell us about you
A short medical intake about your goals and history. A US-licensed clinician reviews it, most within 24 hours. The visit is free.
- 2Made for you
Your prescription
- Written by a US-licensed clinician
- Single-ingredient TB-500
- Licensed 503A pharmacy
Compounded in the USA
Made for you
If your clinician prescribes, a licensed 503A pharmacy fills your prescription for single-ingredient TB-500 acetate in your name.
- 3On its way
Order status
- Prescription approved
- Compounded and inspected
- Shipped discreetly
Discreet delivery
At your door
Your vial and syringes ship within 72 hours of approval, in plain packaging.
- 4Always hereCan we talk about my dose?Of course. I'll review and adjust.
Always adjustable
Ongoing care
Message your clinician any time. Refills, dose changes and pauses run through your account.
Our standard
What HHS requires of the pharmacy
HHS's October 2026 policy sets ten conditions a licensed 503A pharmacy must meet to compound TB-500 for a patient. Here are three of them. No hidden overseas supply chain.
Compounded in the USA
Your TB-500 is filled by a licensed 503A pharmacy in the United States, for you by name. No hidden overseas supply chain.
A tested ingredient
The policy requires the ingredient to come from an FDA-registered facility, with a certificate of analysis for each lot covering identity, purity, endotoxins and heavy metals.
One ingredient, your name on it
Single-ingredient TB-500 acetate, labeled for you, dispensed only on a US-licensed clinician's prescription.
Who it's for
For people who check where their peptides come from
TB-500 through PepScribe is for adults who want it the way any other prescription works: a clinician, a pharmacy and a label with their name on it.
- You've read the thymosin beta-4 research and want TB-500 from a licensed pharmacy
- You've bought research-use-only vials and want to know exactly what's in yours
- You train hard and want a clinician to read your history first
- You want one ingredient, compounded in the USA, with nothing added
TB-500 isn't right for everyone. If your clinician decides it isn't a fit, they'll tell you why, and you're never charged for medication you weren't prescribed.
US-licensed prescribersReal clinicians. Real prescriptions. Real follow-up.
Every TB-500 plan is reviewed and signed by a US-licensed clinician who stays your prescriber of record. Every prescription is filled by a licensed 503A pharmacy in the United States, for you.
- A US-licensed clinician reviews every intake and remains your prescriber
- Compounded in the USA by licensed 503A pharmacies and FDA-registered facilities
- Message your clinician for adjustments throughout your plan
- The online visit is free. You only pay if you're prescribed.
What's been studied. And what hasn't.
Most thymosin beta-4 research is in animals, and most of it used the full 43-amino-acid protein. FDA's drug center recommended against adding TB-500 to the bulks list. FDA's advisory committee voted in favor in July 2026, and HHS pointed to new testing data from FDA-registered manufacturers. Our research library lays out both sides, with sources.
- Licensed 503A pharmacies
- Compounded in the USA
- Sourced research library
503A · Compounded in the USAWhat you receive
What your TB-500 plan includes
One monthly price covers the medication, your clinician and shipping. There is no membership fee, and you see the exact price before anything is billed.
- A free online visit with a US-licensed clinician
- A review of your intake, most within 24 hours
- Single-ingredient TB-500 acetate, if your clinician prescribes it
- Syringes and supplies in the box
- Shipping within 72 hours of approval
- Ongoing access to your clinician for questions and adjustments
Starting from
No membership fee.
Free online visit. You only pay when prescribed.
- Cancel anytime
- No insurance needed
- Discreet shipping
- HSA/FSA eligible
Compounded TB-500 is not an FDA-approved drug. Compounded medications are not reviewed by the FDA for safety or effectiveness. HHS's October 2026 policy is enforcement discretion, which is not FDA approval, and may be revised. Eligibility and dose are determined by a licensed clinician. No specific outcome is promised.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
TB-500 questions
Things people ask before they sign up.
If something is not here, reach out, we'd rather answer it plainly than have you guess.
Is TB-500 FDA-approved?
No. Compounded TB-500 is prepared by a licensed 503A pharmacy for one patient and is not an FDA-approved drug. FDA has not reviewed it for safety or effectiveness. HHS's October 2026 policy lets pharmacies compound it under conditions. That policy is enforcement discretion, which is different from FDA approval.
Is TB-500 the same as thymosin beta-4?
TB-500 is a seven-amino-acid fragment of thymosin beta-4. Most published research studied the full protein, so results from those studies may not carry over to the fragment. Your clinician can walk you through the difference.
How is it taken?
As a subcutaneous or intramuscular injection, on the schedule your clinician sets. Your box includes the syringes.
What if I'm not approved?
The online visit is free, so there is nothing to refund. You are never charged for medication you were not prescribed.
How fast does it ship?
Most intakes are reviewed within 24 hours. After approval, your medication ships within 72 hours.
I compete in a tested sport. Can I use it?
TB-500 is on the World Anti-Doping Agency's prohibited list. A prescription does not change that. Tell your clinician if you are subject to testing.
Can I cancel?
Yes. There are no contracts and no cancellation fees. You can pause or cancel from your account.
Start your TB-500 visit
A few minutes of questions. A US-licensed clinician reads your answers and decides whether TB-500 fits you. The visit is free, and you only pay if you're prescribed.