
GHK-Cu copper peptide cream. A copper tripeptide for the look of skin, aging on its own terms.
GHK-Cu is a naturally occurring copper tripeptide, formulated here as a topical cream and studied for skin firmness, tone, texture, and the look of fine lines. Compounded in the USA by licensed 503A pharmacies. No hidden overseas supply chain.
- Topical cream, applied at home
- Compounded in the USA by licensed 503A pharmacies
- Clinician is prescriber of record
- No hidden overseas supply chain
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.

What it is
A copper peptide, worn on the skin.
GHK-Cu is copper tripeptide-1, a short chain of three amino acids bound to a copper ion. It occurs naturally in the body, where its levels are highest in youth and decline with age. In skin care it has been studied for decades as a topical ingredient, valued for the way it supports the look and feel of mature skin.
PepScribe offers GHK-Cu as a topical cream only. It is applied to the skin or scalp at home and is for external use, not taken by mouth. The cream is compounded for you in the USA by a licensed 503A pharmacy after a clinician reviews your assessment and writes the prescription.
GHK-Cu cream is a compounded preparation. It is not an FDA-approved drug, and it is not marketed here to treat or prevent any disease. The framing is cosmetic and skin-supportive: the look of firmness, the look of tone and texture, the look of fine lines over time.
How it works
What the copper tripeptide is studied to support.
Collagen and elastin support
GHK-Cu has been studied for its role in signaling the skin's fibroblasts, the cells associated with collagen and elastin. Topically, it is used in formulations meant to support the look of firmness and resilience in skin that has lost some over time.
Tone and texture
Copper peptides are a long-standing category in cosmetic chemistry, included in serums and creams formulated to support the appearance of even tone and smoother surface texture. GHK-Cu is among the most studied of them.
Scalp and hair support
GHK-Cu is also formulated for the scalp, where copper peptides have been studied in the context of the look and condition of the hair-bearing skin. Your clinician will discuss whether a facial, scalp, or combined approach fits your goals.
The standard
Compounded in the USA, prescribed by a licensed clinician.
Where your cream is made and who signs off on it is not a footnote. Every GHK-Cu preparation is compounded by a licensed 503A pharmacy in the United States and prescribed by a clinician who has reviewed your assessment. No hidden overseas supply chain.
Made in the USA
Your GHK-Cu cream is compounded in the United States by a licensed 503A pharmacy. No hidden overseas supply chain, and no anonymous gray-market jar shipped from somewhere you cannot name.
Clinician-prescribed
A licensed clinician reviews your assessment and history and remains the prescriber of record. GHK-Cu cream is dispensed on a prescription, not sold as an off-the-shelf cosmetic.
Compounded to your prescription
The cream is prepared for you after your consult rather than mass-produced. Because it is compounded, it is not an FDA-approved drug, and we never imply that it is.

Who it's for
For people thinking about skin as something to maintain, not chase.
GHK-Cu cream is a topical, clinician-prescribed option for adults focused on the look of their skin and scalp over time. A licensed clinician reviews your assessment and history before anything is prescribed. The online visit is free, and you only pay if a clinician prescribes.
- You want a topical, at-home approach rather than a procedure
- Your focus is the look of firmness, tone, texture, or fine lines
- You are interested in copper peptides specifically and want a clinician-reviewed formulation
- You are thinking about scalp and hair-bearing skin alongside your skin care
- You prefer a compounded cream made in the USA over an unverified online purchase
GHK-Cu cream is for external use on adult skin. Share any skin conditions, allergies, pregnancy or breastfeeding status, and current topicals during your assessment so the clinician can decide whether it is appropriate for you.

What you receive
A clinician-prescribed topical, start to finish.
Your plan begins with a free assessment and a clinician review. If GHK-Cu cream is prescribed, here is what comes with it.
- A topical GHK-Cu cream compounded in the USA by a licensed 503A pharmacy
- Clinician review of your assessment, history, and goals
- Application guidance for skin, scalp, or a combined routine
- Prescription written and overseen by a licensed clinician
- Async clinician messaging during your plan
- The ability to pause or cancel at any time
Starting from
Free online visit. You only pay when prescribed.
- Cancel anytime
- No insurance needed
- Discreet shipping
- HSA/FSA eligible
GHK-Cu cream is a compounded topical preparation made by a licensed 503A pharmacy in the USA and is not an FDA-approved drug. It is offered for cosmetic, skin-supportive use and is not intended to diagnose, treat or prevent any disease. It is a topical for external use only. All prescriptions require approval by a licensed clinician. Individual experiences vary.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
GHK-Cu questions
Things people ask before they sign up.
If something is not here, reach out, we'd rather answer it plainly than have you guess.
What is GHK-Cu cream?
GHK-Cu is copper tripeptide-1, a naturally occurring copper peptide formulated here as a topical cream for the skin and scalp. It has been studied as a cosmetic ingredient for its role in supporting the look of firmness, tone, texture, and fine lines. PepScribe offers it as a clinician-prescribed cream, compounded in the USA by a licensed 503A pharmacy.
Is GHK-Cu cream FDA-approved?
No. GHK-Cu cream is a compounded topical preparation made by a licensed 503A pharmacy. Compounded preparations are not FDA-approved drugs, and we never imply that they are. It is offered for cosmetic, skin-supportive use, not to treat any medical condition.
What if I am not approved?
The online visit is free, so there is nothing to refund. You are never charged for a medication you were not prescribed. A clinician may decide it is not the right fit for you, and that is part of responsible care.
How is GHK-Cu cream used?
It is a topical cream applied to the skin or scalp at home, following the routine your clinician recommends. It is for external use only. Your clinician will give you application guidance based on whether your focus is facial skin, the scalp, or both.
What is GHK-Cu studied to support?
In cosmetic research, copper peptides like GHK-Cu have been studied in the context of the look of skin firmness, even tone, surface texture, and fine lines, as well as the condition of the scalp and hair-bearing skin. We describe what the ingredient is studied to support, not guaranteed results, and individual experiences vary.
Where is the cream made?
In the United States, by a licensed 503A pharmacy, after a clinician writes your prescription. No hidden overseas supply chain, and nothing dispensed without a clinician's review and sign-off.
How much does it cost?
The online visit is free. If a clinician prescribes, GHK-Cu cream is from $149/month on the 3-month plan (or $189/month billed monthly). One price includes the medication, clinician care, and shipping. Plans are HSA and FSA eligible.
Who prescribes it and can I cancel?
A licensed clinician reviews your assessment and remains the prescriber of record. You can message your clinician during your plan and pause or cancel at any time.
See if GHK-Cu cream fits your skin goals.
A short, free assessment. A licensed clinician reviews it and decides what is appropriate. The online visit is free, and you only pay if you're prescribed.