Estradiol, the estrogen at the center of menopause care.
Estradiol is the main estrogen your body makes less of through the menopausal transition. A US-licensed clinician reviews your symptoms and, where indicated, your labs, then prescribes bioidentical estradiol only when it fits your history. Compounded in the USA by licensed 503A pharmacies. No hidden overseas supply chain.
- Clinician-led, US-licensed
- Bioidentical estradiol
- Labs reviewed where indicated
- Compounded in the USA by licensed 503A pharmacies
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
What it is
The estrogen your body makes less of, prescribed as real medical care
Estradiol is the primary form of estrogen in the body, and its decline drives many of the recognized changes of perimenopause and menopause. Bioidentical estradiol is structurally identical to the estradiol your body produces, and your clinician can prescribe it as an oral form for whole-body symptoms or a vaginal form focused on local symptoms, depending on your picture.
This is a clinical process, not a product off a shelf. A US-licensed clinician reviews your history and, where it informs the decision, your labs, and writes a prescription only when the medical picture supports it. If you have a uterus, estradiol is typically prescribed alongside progesterone to protect the uterine lining. Every dose is compounded in the USA by a licensed 503A pharmacy. Compounded estradiol is not an FDA-approved drug.
How it fits your plan
Form, pairing, and monitoring
Oral or vaginal
Your clinician selects the form from your symptoms. An oral form addresses whole-body symptoms such as hot flashes and night sweats; a vaginal form focuses on local symptoms such as dryness. The choice is a clinical one, made with you.
Paired with progesterone when needed
For women with a uterus, estrogen is prescribed together with progesterone to protect the uterine lining. Your clinician manages this pairing so your plan is complete rather than piecemeal.
Reviewed and adjusted
Where it informs the decision, your clinician reviews estradiol and related labs, and adjusts the form or dose over time as your symptoms and history evolve. HRT is an ongoing relationship, not a one-time order.
Sourcing and safety
Bioidentical, US-compounded, and prescribed by a clinician of record.
From who writes the prescription to where your estradiol is compounded, the chain behind your medication is transparent by design.
A clinician of record
A US-licensed clinician reviews your intake, discusses the trade-offs and the medical evidence, and is your prescriber of record. Your estradiol is never sold off a shelf.
Compounded in the USA
Your bioidentical estradiol is compounded in the USA by a licensed 503A pharmacy under your prescription. No hidden overseas supply chain.
Labs where indicated
Where it informs the decision, your clinician reviews estradiol and related hormone panels so your plan reflects what your body is missing.
Who it's for
For women navigating the estrogen decline of menopause, who want a clinician who listens.
Estradiol is considered for women with symptoms of the menopausal transition, reviewed against their history and, where indicated, their labs. Eligibility is a clinical decision made by your prescriber.
- Hot flashes, night sweats, or disrupted sleep that track with the menopausal transition
- Vaginal dryness or local symptoms that affect comfort and intimacy
- Mood, focus, or energy changes you want evaluated as part of the hormonal picture
- You want bioidentical estrogen prescribed and monitored, not sourced off a shelf
Your clinician reviews your history for contraindications including a personal history of hormone-sensitive cancers, blood clots, or cardiovascular disease, and prescribes only when the evidence supports it. Not everyone qualifies, and if estradiol is not appropriate you are never charged for a medication you were not prescribed.
What you receive
One plan. Everything included.
A flat monthly price covers your compounded medication, the clinical care, and shipping. Your clinician sets the exact form and dose during your review and adjusts it over time.
- Bioidentical estradiol prescribed for you, oral or vaginal, US-licensed
- Compounded in the USA by a licensed 503A pharmacy
- Progesterone pairing where clinically indicated
- Lab review where indicated, including hormone panels
- Async messaging with your care team and dose adjustments over time
- Cancel or pause anytime
Starting from
Free online visit. You only pay when prescribed.
- Cancel anytime
- No insurance needed
- Discreet shipping
- HSA/FSA eligible
Compounded estradiol is not an FDA-approved drug. Bioidentical hormone therapy is not appropriate for everyone. Form, dose, and any companion hormones are determined by a licensed clinician based on your history and, where indicated, your labs.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
Estradiol questions
Things people ask before they sign up.
If something is not here, reach out, we'd rather answer it plainly than have you guess.
What is bioidentical estradiol?
Estradiol is the main estrogen your body produces. Bioidentical estradiol is structurally identical to it, compounded in the USA by a licensed 503A pharmacy under your prescription. It is prescribed by a US-licensed clinician and is not an FDA-approved drug.
Is it taken orally or vaginally?
Both forms exist, and your clinician selects the one that fits your symptoms. An oral form addresses whole-body symptoms such as hot flashes; a vaginal form focuses on local symptoms such as dryness. Your clinician decides with you.
Do I need progesterone too?
If you have a uterus, estrogen is typically prescribed alongside progesterone to protect the uterine lining. Your clinician manages this pairing as part of a complete plan.
Will my labs be reviewed first?
Where it informs the decision, yes. Your clinician may review estradiol and related hormone panels so your plan reflects what your body needs. Lab review is part of treating menopause as a real medical conversation.
How much does it cost?
The online visit is free. If a clinician prescribes, the program is $139/month on the 3-month plan ($417 billed every 3 months), covering the medication, clinician care, and shipping. Plans are HSA and FSA eligible.
Menopause is a medical conversation.
Take the free assessment. A US-licensed clinician reviews your symptoms and, where indicated, your labs, then prescribes bioidentical estradiol only when it fits. The online visit is free, and you only pay if you're prescribed.