Oral semaglutide. GLP-1 therapy in a daily tablet, no injections.
Compounded oral semaglutide, prescribed by licensed clinicians when clinically appropriate. The GLP-1 class you know, in a once-daily tablet instead of a weekly shot.
- No injections
- Clinician-led
- Compounded in the USA by licensed 503A pharmacies
- Free online visit
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
What it is
GLP-1 therapy, in a tablet you take by mouth
GLP-1 medications are part of the conversation around weight management, and for many people the weekly injection is the one thing that has kept them from starting a clinician-led plan. Oral semaglutide is a compounded tablet form of the GLP-1 class, taken once daily by mouth. No injections.
This is compounded oral semaglutide, not the branded oral pill and not a generic of any brand-name product. It is compounded in the USA by licensed 503A pharmacies under a prescription from your assigned clinician. No hidden overseas supply chain. Compounded medications are not FDA-approved, and your clinician prescribes it only when it is clinically appropriate for you.
What changes here is the format and the access: a daily tablet, reviewed and prescribed by a licensed clinician, with eligibility, labs, and monitoring handled as part of the plan.
How it works
The mechanism behind oral semaglutide
GLP-1 receptor agonism
Semaglutide is designed to mimic a hormone your body already produces after eating. It binds to GLP-1 receptors involved in appetite regulation, working with your body's existing satiety signaling rather than against it.
Appetite and gastric emptying
By engaging these pathways, GLP-1 therapy acts on the signaling involved in fullness and slows gastric emptying. Your clinician titrates the dose gradually based on your response and tolerability.
A once-daily oral routine
Instead of a weekly subcutaneous shot, the compounded form is taken as a daily tablet by mouth. Your clinician reviews your history, sets a starting dose, and adjusts over time. Labs and monitoring remain part of the plan.
Sourcing and safety
Where your medication comes from.
Sourcing matters. Every dose is compounded in the USA by licensed 503A pharmacies. No hidden overseas supply chain.
Compounded in the USA
Your oral semaglutide is compounded in the USA by licensed 503A pharmacies, not packaged here after being made elsewhere. No hidden overseas supply chain.
Quality standards
Preparations are made under USP 795 standards for nonsterile compounding, with batch-level testing per the partner pharmacy's protocol.
Clinician of record
A licensed clinician reviews your history, decides whether oral semaglutide is appropriate, and remains your prescriber of record. Prescribed only when clinically appropriate.
Who it's for
Convinced about GLP-1, and stuck on the needle.
If you already know GLP-1 therapy and have held off for one reason, an oral plan may be worth a clinician's review.
- You are interested in medical weight management but the weekly injection has kept you from starting
- You prefer a daily tablet over a weekly shot
- You have a BMI of 27 or higher with a weight-related health concern, or a BMI of 30 or higher
- You want a clinician-led plan with eligibility review, labs, and monitoring rather than a self-directed approach
- You want a US-compounded option and care about where your medication comes from
Your PepScribe clinician makes the final call on eligibility based on your health history and goals. The online visit is free, and you only pay if a clinician prescribes. You are never charged for medication you weren't prescribed.
What you receive
What an oral semaglutide plan includes
A clinician-led plan built around a once-daily oral form. Your online visit is free. You only pay if a clinician prescribes, and one monthly price then covers the medication, the clinical care, and shipping.
- A clinical assessment reviewed by a licensed clinician
- A personalized eligibility decision for oral semaglutide
- Compounded oral semaglutide when prescribed, shipped from a licensed 503A pharmacy
- Dose guidance and titration from your care team
- Ongoing monitoring and the ability to message your clinician about side effects or adjustments
- Clear guidance on any labs your clinician may request
Starting from
Free online visit. You only pay when prescribed.
- Cancel anytime
- No insurance needed
- Discreet shipping
- HSA/FSA eligible
Compounded oral semaglutide is not an FDA-approved drug, and it is not the same as any branded oral GLP-1 product. Compounded GLP-1 availability can change with FDA shortage status. If the oral form is unavailable, your clinician can offer the injection form, and you may decline for a full refund. All prescriptions require approval by a licensed clinician, and individual results may vary.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
Oral Semaglutide questions
Things people ask before they sign up.
If something is not here, reach out, we'd rather answer it plainly than have you guess.
Is this a branded GLP-1 medication or a generic version of one?
No. This is compounded oral semaglutide, prepared by a licensed 503A pharmacy. It is not a branded product, not the branded oral pill, and not a generic of any brand-name medication. It is in the same GLP-1 class, but we do not equate it to any specific branded drug.
Is oral semaglutide FDA-approved?
No. Compounded medications, including oral semaglutide, are not FDA-approved. It is compounded by licensed 503A pharmacies in the USA under a prescription from your clinician, and your clinician prescribes it only when it is clinically appropriate for you.
What happens if I am not approved?
The online visit is free, so there is nothing to refund. You are never charged for a medication you were not prescribed. A clinician may decide it is not the right fit for you, and that is part of responsible care.
Is there really no injection?
The plan on this page is a once-daily tablet taken by mouth, so there are no injections. Your clinician may still ask for labs as part of responsible care. If the oral form becomes unavailable due to supply, your clinician can offer the injection form, which you are free to decline for a full refund.
Can I get oral semaglutide without a prescription?
No. Oral semaglutide requires a prescription. A licensed clinician reviews your health history, confirms eligibility, and remains your prescriber of record. There is no way to obtain it without that review.
How much does oral semaglutide cost?
The online visit is free. If a clinician prescribes, oral semaglutide is from $99/month on the 3-month plan (or $149/month billed monthly), after clinician approval. One price includes the medication, clinician care, and shipping. Plans are HSA and FSA eligible, and subject to supply availability.
How is oral semaglutide different from oral tirzepatide?
Both are taken as a daily tablet. Semaglutide acts on the GLP-1 pathway. Tirzepatide acts on two pathways, GLP-1 and GIP. We offer oral tirzepatide on its own page, and your clinician helps determine which is appropriate for you based on your history and goals.
Will I have to switch to injections later?
Not by default. The plan is built around the oral form. Because compounded GLP-1 availability can change with FDA shortage status, if the oral form is unavailable your clinician can offer the injection form. You may decline that switch for a full refund.
GLP-1 therapy, without the needle holding you back.
Take a few minutes to see whether a daily oral semaglutide plan is appropriate for you. The online visit is free, and you only pay if a clinician prescribes.