Sermorelin. Support what your body already does.
A growth-hormone-releasing hormone (GHRH) analog that signals your pituitary to release GH naturally. Daily subcutaneous injection, typically before bed. Compounded in the USA by licensed 503A pharmacies.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
Sermorelin pricing
RxOne plan. Everything included.
Sermorelin is dosed in a single nightly subcutaneous step. Your clinician sets the exact unit dose during your consult based on your intake.
Single dose
Nightly subcutaneous
$129/month
Includes clinician care, syringes, and shipping.
$49 consult fee, refunded as your first-month credit if your clinician approves you, or refunded in full if no prescription is issued.
Auto-renews monthly after clinician approval. Pause or cancel any time before your next ship date. 48-hour refund window on first charge.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
What it is
A GHRH analog, not synthetic HGH.
Sermorelin is a short peptide whose amino-acid sequence corresponds to an active fragment of natural GHRH, the hypothalamic hormone that tells your pituitary to release growth hormone. It was originally developed in the 1980s as a diagnostic and therapeutic for pediatric growth-hormone deficiency.
What makes sermorelin different from synthetic HGH: it works withthe pituitary instead of bypassing it. Synthetic GH just floods the system. Sermorelin nudges the pituitary to do its own job, which keeps the body’s natural feedback loops intact.
Compounded sermorelin is prepared by a US-licensed 503A pharmacy under your clinician’s prescription, not 503B, not international.
How it works
Mechanism of action.
Pulsatile GH release
Binds GHRH receptors in the anterior pituitary, prompting natural pulsatile growth-hormone release rather than a constant flood.
Preserves feedback loops
Works with the hypothalamic-pituitary axis' native negative feedback, the pituitary backs off when somatostatin signals rise.
Recovery, sleep, body composition
Elevated endogenous GH/IGF-1 supports tissue repair, deeper sleep architecture, and body composition over months of consistent use.
Who it’s for
Clinician-reviewed, not everyone qualifies.
A licensed clinician reviews your intake and recommends sermorelin only when appropriate. Free assessment. Your consult fee credits toward your first month if approved, or refunded in full if no prescription is issued.
- Considered for adults with goals around recovery, sleep quality, and body composition
- Your clinician reviews your history for pituitary, thyroid, and endocrine contraindications
- Not prescribed during pregnancy, active cancer, or known pituitary disease
- Labs may be ordered before prescribing; results inform dosing
What comes with the plan
Everything included.
- Clinician-prescribed, US-licensed
- Compounded in the USA by a licensed 503A pharmacy
- Flat monthly pricing, medication included
- Supplies and injection instructions
- Async clinician messaging
- Cancel or pause anytime
Compounded medications are prepared by licensed 503A pharmacies in the USA and are not FDA-approved. All prescriptions require approval by a licensed healthcare provider. Individual results may vary.
Start a Sermorelin plan.
Three-minute assessment. Clinician review within 48 hours. Your consult fee credits toward your first month if sermorelin is prescribed.