Semaglutide. The GLP-1 everyone’s talking about.
A GLP-1 receptor agonist that works with your body’s appetite-regulation system. Weekly subcutaneous injection. Compounded in the USA under 503A rules for patients who clinically qualify.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
Dose-banded pricing
RxPick the plan your clinician prescribes.
Compounded semaglutide is dosed in titration steps. Your clinician selects the band based on your intake, history, and response. Lower doses are where most patients start.
Starter
0.25 – 0.50 mg
$199/month
Standard
1.0 – 1.7 mg
$249/month
Maintenance
2.4 mg
$299/month
$49 consult fee, refunded as your first-month credit if your clinician approves you, or refunded in full if no prescription is issued.
Auto-renews monthly after clinician approval. Pause or cancel any time before your next ship date. 48-hour refund window on first charge.
Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Rx required.
What it is
A GLP-1 receptor agonist, compounded for qualifying patients.
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Originally developed as a therapy for type 2 diabetes, it is now widely used for weight management because of its effect on appetite regulation and glucose control.
The branded injectable forms are FDA-approved finished drugs. Compounded semaglutide is a different thing: prepared by a US-licensed 503A pharmacy under a clinician’s prescription, for patients with documented clinical need under the “not essentially a copy” framework. It is not FDA-approved.
Because the FDA injectable shortage has resolved, compounded semaglutide is now a specialty line at PepScribe, prescribed when a compounded formulation is clinically appropriate, not as a generic substitute for the branded product.
How it works
Mechanism of action.
GLP-1 receptor agonism
Binds and activates GLP-1 receptors in the pancreas, brain, and GI tract, mimicking the body’s own post-meal satiety and glucose-regulation signaling.
Appetite suppression
Signals to the hypothalamus to reduce hunger and increase satiety. For many patients the subjective change is quieter food noise and longer fullness after meals.
Slower gastric emptying
Slows the rate at which the stomach empties, extending the physical sensation of fullness and flattening post-meal blood-sugar curves.
Who it’s for
Clinician-reviewed, not everyone qualifies.
A licensed clinician reviews your intake and recommends semaglutide only when clinically appropriate under 503A compounding rules. Free assessment. If it’s not a fit, you aren’t charged.
- Considered for adults with clinical eligibility for GLP-1 therapy
- Your clinician reviews your history for thyroid conditions (MTC/MEN2), pancreatitis, and pregnancy
- Not prescribed during pregnancy, active thyroid malignancy, or certain GI conditions
- Labs and vitals may be ordered; results inform dose selection and adjustments
What comes with the plan
Everything included.
- Clinician-prescribed, US-licensed
- Compounded in the USA by a licensed 503A pharmacy
- Flat monthly pricing, medication included
- Supplies and injection instructions
- Async clinician messaging
- HSA and FSA eligible
Compounded semaglutide is prepared by licensed 503A pharmacies in the USA and is not FDA-approved. The branded injectable GLP-1 products are separate FDA-approved drugs produced by their manufacturers. All prescriptions require approval by a licensed healthcare provider. Individual results may vary.
See if Semaglutide is a fit.
Three-minute assessment. Clinician review within 48 hours. You aren't charged unless semaglutide is prescribed.