How the pricing models differ
As of July 2026, Hims prices weight loss with a Hims Weight Loss Membership at $39 for the first month and then $149 per month. Per its own pages, that membership is billed separately from the medication and does not include or guarantee a prescription. Branded GLP-1 medication is charged on top of the membership.
So the number that decides the bill is membership plus medication, not the membership alone. Checked August 2026, Novo Nordisk's NovoCare self-pay price for Wegovy is $349 per month for the 0.25 mg through 2.4 mg doses, with a $199 introductory price covering the first two months, and $149 per month for the oral 1.5 mg. Eli Lilly's LillyDirect self-pay price for Zepbound is $299 at 2.5 mg, $399 at 5 mg, and $449 from 7.5 mg through 15 mg. Add the $149 monthly membership and a patient paying cash is at roughly $298 per month on the oral, $498 per month on the Wegovy injection, and $598 per month on Zepbound at a maintenance dose.
PepScribe charges no separate membership fee for its peptide plans. One flat monthly price includes the medication, clinician oversight, supplies, and shipping, and you see the exact monthly price before anything is billed. Compounded semaglutide is $198 to $298 per month and compounded tirzepatide is $328 to $548 per month, depending on your prescribed dose, across a peptide range that runs from $159 to $548. The online visit is free, and you only pay if a clinician prescribes. Compounded medications are not FDA-approved.
Compounded vs branded GLP-1s
As of July 2026, Hims lists branded GLP-1 medications for weight loss and does not list compounded semaglutide. PepScribe offers compounded semaglutide and compounded tirzepatide, prescribed by a US-licensed physician and compounded in the USA by licensed 503A pharmacies.
Compounded medications are not FDA-approved. Compounded semaglutide is compounded semaglutide: it is prepared by a licensed 503A pharmacy under an individual prescription and is not the same as, or a substitute for, any branded FDA-approved drug. A clinician decides whether a compounded or branded option is appropriate for a given patient.
Pharmacy sourcing
PepScribe publishes a single sourcing standard: every dose is compounded in the USA by licensed 503A pharmacies, not 503B and not international. No hidden overseas supply chain. Hims has said in its newsroom that it operates its own 503A pharmacies and a 503B outsourcing facility. Both are legitimate US models; they are simply different, and PepScribe’s standard is 503A-only.
Scope of care
Hims is a broad telehealth brand spanning weight loss, sexual health, hair, skin, and mental health. As of July 2026, its newsroom describes peptides as an area it is exploring, and it does not offer Sermorelin or NAD+. PepScribe is a peptide-therapy practice: alongside compounded GLP-1s for weight management, it offers peptide therapies such as Sermorelin and NAD+, plus testosterone therapy, hormone therapy, sexual health, hair, and skin through its treatments.
Verification and certification
PepScribe is a LegitScript-certified healthcare merchant (certificate ID 49946300), which you can confirm on the trust page or directly on LegitScript. For a category-level view of how PepScribe’s model differs from other peptide options, see how PepScribe compares.
Hims is a trademark of its owner. PepScribe is not affiliated with or endorsed by Hims.
Frequently asked questions
What is the main difference between PepScribe and Hims for weight loss?
The pricing model. As of July 2026, Hims sells its weight-loss program through a Hims Weight Loss Membership ($39 for the first month, then $149 per month) that is billed separately from the medication and, per its own pages, does not include or guarantee a prescription. Adding the medication at its published self-pay price puts a cash-paying patient at roughly $298 to $598 per month, against $198 to $298 per month for PepScribe’s compounded semaglutide with everything included. PepScribe charges no separate membership fee: one flat monthly plan price includes the medication, clinician oversight, and shipping. Hims offers branded GLP-1s; PepScribe offers compounded semaglutide and compounded tirzepatide, which are compounded medications and not FDA-approved.
Does Hims offer compounded semaglutide as of July 2026?
As of July 2026, Hims lists branded GLP-1 medications (such as Wegovy and Zepbound) for weight loss and does not list compounded semaglutide. PepScribe offers compounded semaglutide and compounded tirzepatide prescribed by a US-licensed physician and compounded in the USA by licensed 503A pharmacies. Compounded medications are not FDA-approved.
How does pharmacy sourcing differ?
PepScribe uses one standard: every dose is compounded in the USA by licensed 503A pharmacies, not 503B and not international. No hidden overseas supply chain. Hims has said in its newsroom that it operates its own 503A pharmacies and a 503B outsourcing facility. These are different fulfillment models; PepScribe publishes a 503A-only standard.
Is PepScribe or Hims cheaper for weight loss?
They price differently, so the honest answer is that it depends on the plan. As of July 2026, Hims charges a membership ($39 first month, then $149 per month) on top of the medication cost. PepScribe charges one flat monthly price that already includes the medication, oversight, and shipping, with peptide plans running from $159 to $548 per month depending on the therapy and prescribed dose. Compare the total monthly cost, not just the membership line.
Which one should I choose?
They are different models for different needs. Hims is a broad telehealth brand with branded GLP-1 medications sold alongside a membership. PepScribe is a peptide-therapy practice offering compounded GLP-1s plus other peptide therapies, with a free online visit and one flat monthly price. A US-licensed clinician determines whether any treatment is appropriate for you.
